Tuesday, December 8, 2009

What are the top nephrology stories of the last decade?

As we come to the end of the naughts, we naturally reflect back and think about how far we have come from in the last ten years. Here is my quick list:
  1. MYH9 gene for ESRD
  2. The failure of the normalization of hemoglobin and the wholesale reevaluation of ESAs
  3. The rise of aldosterone and its importance in hypertension and renal disease
  4. the failure of dialysis dose to improve out come in both chronic (HEMO) and acute dialysis (ATN).
  5. FGF-23, hey a whole new hormone and a major advancement in renal physiology
  6. Re-emergence of home dialysis
  7. Problems with the definition of CKD and the problems with eGFR
  8. discovering the antigen in idiopathic membranous nephropathy
I want to do a longer article about this but I'm sure I'm missing some stuff. I don't have a transplant subject, seems like vitamin D belongs up there, what about the phos binder wars? Bundling? What about MMF in lupus nephritis and every other GN?
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