Tuesday, January 13, 2009

Has anybody seen this?

I have two patients who routinely have significantly lower spot protein to creatinine ratios as compared to 24-hour urine for protein.

The urine electropheresis shows non-specific proteinuria.
  • The first patient is an obese young African American woman with WHO type V lupus nephritis.
  • The other patient is a thin young Caucasian woman with secondary FSGS due to chronic reflux. Her most recent PCR is 1.7, and her 24-hour urine from one week prior is 4.9 g.

Any ideas? What am I missing?
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