Must know facts about albumin! Number seven will blow you away!

Albumin is made in hepatocytes at a rate of 200 mg/kg/day - Created with Haiku Deck, presentation software that inspires

Improving albumin levels among hemodialysis patients

1. Albumin is made in hepatocytes at a rate of 200 mg/kg/day 
1. or 14 g in 70 kg person
2. Total body albumin is 4-5 g/kg
3. 40-45% of albumin is in the intravascular space
4. Normal albumin concentration in the interstitial space is 
1. 0.7 in fat and 
2. 1.3 in skeletal muscle
5. Albumin has a half life of 2 to 3 weeks
6. The drop in albumin with inflammation is due to: 
1. reduced synthesis and 
2. increased fractional catabolic rate (FCR)
7. Intradialytic weight gain of 2.8 liters (4% in a 70 kg man) will dilute the albumin down 0.8 g/dL 

Refs

Improving albumin levels among hemodialysis patients (PubMed)

Measurement of interstitial albumin in human skeletal muscle and adipose tissue by open-flow micro perfusion (PubMed)